Epistane Info & Products

Epistane Cycle Guide & Information


What is Epistane?

Epistane is a DHT derived prohormone that was brought to market by RPN with their product "Havoc." Epistane is an anti-estrogenic dry compound that will aid users in adding lean muscle mass as well as cutting fat. In addition to this, Epistane does not aromatize and is non-progestagenic. This basically means that while on Epistane, estrogen related side effects like gyno and progesterone related side effects like sensitive breast tissue are virtually non-existent. .

What are the different names/ways of writing Epistane?


The nomenclature for Epistane can be written two different ways, 2a,3a-epithio17a methyl-17b-hydroxy-5a-androstane or 2a,3a-epithio-17a-methyl-5a-androstan-17b-ol. Epistane has also been referred to as Epi, and the most common misspelling is Epistain. 

How does Epistane increase lean muscle mass?

Epistane also binds to androgen receptors in skeletal muscle cells and muscle stem cells. This leads to changes in muscle cell function and protein synthesis. In the case of muscle stem cells, which will actually change and fuse with your active adult skeletal muscles increasing the muscles potential for growth and repair. On the opposite side, the presence of androgens actually decreases the ability of stem cells to form new fat cells. So now have increased stem cell conversion to muscle cells and decrease the conversion of stem cells to fat cells, giving you more positive effects of nutrition and training.


Do I need take On Cycle Support while cycling Epistane?

Epistane is a methylated prohormone so it is liver toxic, which means taking cycle support is necessary while cycling Epistane. A cycle support like Protex by Vital Labs will be sufficient for an Epistane cycle. 


Do I need to run a Post Cycle Therapy (PCT) after my cycle of Epistane? 

PCT is mandatory after any prohormone cycle. Keep in mind that you body will be used to its hormone levels being very high from Epistane, which means your body's natural production of testosterone will be very low. In addition to this you body's organs have been working extremely hard to process the prohomormones, and will need to be rejuvenated. Check out our Top 5 Post Cycle Therapy products, as they will all aid in this as well as help normalize your estrogen production.

Pulse Cycle Epistane, what does it mean and should I do it?

Pulse cycling refers to intentionally running a cycle at a lower dosage with the intention of reducing the probability of encountering side effects, both long term and short term. An example of this lets say you run an Epistane cycle at 30mg a day over the course of 30 days, and end up gaining 10lbs of lean mass, but you get really achy joints from it. Now for a pulse cycle, let's say you just run Epistane at 10mg per day, a third of the dosage that you would normally do. In theory you would be able to achieve a third of the results and a third of the side effects, so you would gain roughly 3-4lbs over that 30 day period and experience little to no joint pain at all. The benefit to this is that you can run a longer cycle, and experience good gains while mitigating side effects. An additional benefit to this is that your body can get itself back to normal much easier and faster, although PCT is still necessary. 


 How do you dose Epistane? 

Epistane can be dosed in a variety of ways. Many people like to ramp up their dosages. Beginners like to start at 20mgs a day for 30 days. Intermediate generally run 20/30/30/30 or 20/30/30/40. Advanced users we have seen run 30/40/40/40. These are just observations and it is wise to see how it feels and trust what your body is telling you. Many Epistane supplements like to provide 10 mg pills for easy dosing. Of course your dosing should be ran with On cycle, and the Epistane pills should be taken separately throughout the day. For example, if you are running 30mgs of Epistane daily, take 3 doses of 10mgs each spread throughout the day. 

Will I get gyno when taking Epistane?

Generally speaking you should not get gyno from running an Epistane cycle. People who have gyno have ran cycles of Epistane at a really low dosage, 5-10mg per day to help reduce gyno. 
Although very uncommon, some users have developed gyno during their PCT or after their PCT, this is known as rebound gyno. This can happen to users who run Epistane at very high dosages (50mg+) because Epistane actually blocks estrogen. If you are running Epistane at a very high dosage, your body will want to produce/convert estrogen to normalize its hormone levels, but Epistane will block this from happening. So what can potentially happen is that when you are on your PCT and no longer have Epistane in your system blocking estrogen, your body can produce and too much estrogen due to being suppressed while your test levels are so high. If you are gyno prone or are running a cycle of Epistane at a very high dosage, we suggest you use Estrogenex by Hi-Tech Pharmaceuticals with your PCT. 

How harsh is Epistane on the liver/body?

Epistane is actually one of the least tough prohormones on the liver and body. It still needs to be run with on cycle support, but as a result of its lower toxic load users like to increase dosage and run times of their cycles to optimize results. 

Epistane side effects, what are they? 

The Epistane side effects are very low. Overall, Epistane side effects are very uncommon when while on cycle. The reason for this is the build of Epistane making it anti-estrogenic. As a result you do not have to worry about gyno. There are still the usual sides that you would get with any prohormone cycle, like, lethargy, dry joints, and sometimes back pumps. Epistane is a dry mass gainer so if you run high doses it can take a toll on the joints. We recommend taking a proper on cycle and adding a joint supplement to offset the joint dryness. One of the ore uncommon epistane side effects is rebound gyno, which is when your body develops gyno during your PCT order after. This is typically due to running an epistane cycle at a very high dosage (40 mg+) and then abruptly stopping. To avoid this Epistane side effect, we suggest you dial down the dosage to 10=20 mg in your last few days/week.

I want to stack Epistane with another prohormone to maximize my gains, what does Epistane stack best with? 

Epistane is a great prohormone for stacking; this is due to its anti-estrogenic qualities as well as its low toxicity profile. Many people stack Epistane with halodrol as this will add more strength and lean hard muscle. Some stack Epistane with methylstenbolone as methylsten adds good size gains, alongside with Epistane to reduce estrogen and harden the muscle gains. These are just two options; we have seen people stack Epistane with almost all other prohmormones. You should look at your ultimate goal first and analyze the benefits that running an Epistane cycle will provide and consider that in conjunction with your secondary prohormone. Please note that stacking is not for beginners and on cycle support must be taken with your stack. 

Epistane Product Reviews:


Great for beginners!    Reviewed by Andrew -  RPN Havoc

I started this cycle weighing 160lbs. Im 5'8 and wanted to overcome my current plateau. By the way this was my first cycle ever. My bench went from 3 sets of 225 at 8 reps to 250, and my max went from 275 to 300. I really enjoyed my cycle of havoc, all my buddies are taking dimethavar, but aren't Able to keep gains. I have been able to maintain my gains and I'm starting to feel my strength increase once again as I'm taking my pct. Weight 175! No side effects, other than feeling a little bit moody, but nothing uncontrollable.

Highly recommended!    Reviewed by Alex - Epi-10 by LGI

I Ran LGI EPI-10 solo for six weeks, 30/40/40/40/50/50... I Gained about 10 lbs of lean mass, muscles felt way fuller. Pumps were amazing! Strength was thru the roof! I see veins now that I've never seen before.. Besides sensitive nips, side-effects were pretty much non existent.. Nips went back to normal immediately starting PCT.. Overall excellent product.

Epistane Products:

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What is the Best Prohormone?

That ultimately depends on you! If you have never done a cycle before, the best prohormone for you will be one that is a single compound, meaning a product that has just one prohormone in it.

If you an experienced prohormone user, you may need a two compound prohormone or more! You may need to try a different prohormone compound to see if your body responds better.

You need to ask yourself one question first!

What is my goal in taking prohormones?

Bulking Prohormones - I Want To Get HUGE!

So you are looking to add on 10-15 lbs? If you are looking to bulk up and add on lean mass, check out our Top 10 Bulking Prohormones. This list ranks the top bulking prohormones in the industry based on customer feedback, prohormone logger results, our pro support team’s experience, and repeat sales.

If you want to see more than just the Top 10, check out our Bulking Prohormones Category.

If you would like to learn more about bulking prohormones, check out these information pages:

Bulking Prohormone Info




Cutting Prohormones - I Want to Get Shredded!

So you are looking to shred that layer of fat and show off your physique? Then check out our Top 10 Cutting Prohormones. This again is another list that ranks the top cutting prohormones in the industry based on customer feedback, prohormone logger results, our pro support team’s experience, and repeat sales.

If you want to see more than just the Top 10, check out our Cutting Prohormones Category.

If you would like to learn more about cutting prohormones, check out these information pages:

Cutting Prohormone Info




Prohormone Stacks - I Want It All!

So you want us to hand you it all on a silver platter? Well we have done it! Our prohormone stacks have all been carefully engineered for optimal results, and we have rated them for you with the Top 5 Prohormones Stacks.

If you want to see more than just the Top 5, check out our Prohormones Stacks Category.

What else do I need when taking Prohormones?

On Cycle Support

During any cycle it is necessary to take an on cycle support to help protect your body during your cycle. Prohormones are toxic and your body will be working extremely hard to process everything.

Check out the best on cycle support products with our Top 5 On Cycle Support Products or you can see all cycle supports in our On Cycle Support Category.

Post Cycle Therapy

Every cycle needs to be followed by Post Cycle Therapy (PCT) to help normalize your hormone levels, rejuvenate your body and help you keep your gains.

Check out the best PCT products with our Top 5 Post Cycle Therapy Products or you can see all PCT supplements in our Post Cycle Therapy Category.

Estrogen Blocker

In some cases it is necessary to take an estrogen blocker to prevent negative side effects. Check out our Estrogen Blocker Information page to learn when it is right for you.

Check out our best estrogen blockers with our Top 5 Estrogen Blockers or you can see all estrogen blockers in our Estrogen Blocker Category.

You are always welcome to Contact Our Pros for support with your cycle!

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